



- Case Study42 year old Female
Symptoms Dark Circles Under The Eyes Treatment Name Skin Rejuvenate Injections (under the eyes) Approximate Rates 89,000 JPY for both sides (excluding tax) Risks of the procedure In rare cases, internal bleeding and swelling may occur. - Case Study28 year old Female
Symptoms Sloping forehead Treatment Name Skin Rejuvenate Injections (forehead) Approximate Rates 198,000 JPY (excluding tax) Risks of the procedure In rare cases, internal bleeding and swelling may occur. - Case Study28 year old Female
Symptoms Nascent lines Treatment Name Skin Rejuvenate Injections (nascent lines) Approximate Rates 89,000 JPY (excluding tax) Risks of the procedure In rare cases, internal bleeding and swelling may occur.


- Case Study24 year old Female
Symptoms Open pores Treatment Name Microneeding skin treatment (cheek) Approximate Rates 27,000 JPY (excluding tax) Risks of the procedure In rare cases, internal bleeding and swelling may occur. - Case Study26 year old Female
Symptoms Open pores Treatment Name Microneeding skin treatment (around the nose) Approximate Rates 27,000 JPY (excluding tax) Risks of the procedure In rare cases, internal bleeding and swelling may occur. - Case Study34 year old Female
Symptoms Open pores, dull skin and craters Treatment Name Microneeding skin treatment (entire face) Approximate Rates 84,500 JPY (excluding tax) Risks of the procedure In rare cases, internal bleeding and swelling may occur.


Regeneration of skin cells using the body's own blood
Skin Rejuvenate Injections, Microneeding skin treatment is an aesthetic skin regeneration treatment that uses multi-visceral blood vessels extracted from your own blood. Platelets contain high levels of natural growth factors, which activate various cells to regenerate and repair the tissue. As your own skin cells regenerate, the effect lasts for a long time, 3-4 years or more.


Microneeding skin treatment uses a derma pen to create a myriad of microscopic holes in your skin to deliver PRP to the dermis and into the guilette. The synergistic effects of the dermis's self-damaging power and PRP's ability to produce beautiful skin components dramatically repair aging and acne-prone skin.
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A derma pen is used to make microscopic holes in the dermis.
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Penetration of PRP into the hole and introduction of PRP into the dermis
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It increases the regenerative capacity of the dermis and renews the skin.


The PRP used in Skin Rejuvenate Injections and Microneeding skin treatment is created by our own original method. Therefore, please note that even if you find similar treatments at other clinics, they may be fundamentally different from our treatments.
Symptoms that can be improved with Skin Rejuvenate Injections and Microneeding skin treatment
This is the ultimate skin rejuvenation treatment, suitable for treating a wide variety of customes using your own blood, which is highly effective in improving skin quality with fewer allergic reactions. The production of collagen and elastin, which are the building blocks of the skin, is activated, resulting in natural volume growth and freshness and firmness.








Growth factors act in the fatty dermal layer of the dermis where PRP is injected to promote collagen and capillary growth, which gradually improves the appearance of depression and skin texture.


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The Skin Regeneration Effect Lasts more than 3 years!
Skin Rejuvenate Injections and Microneeding skin treatment lasts for 3 or 4 years, due to your own skin regenerating itself, with the dents and the improved skin texture lasting for 3 or 4 years, even if we say 3 or 4 years, the effect does not wear off like hyaluronic acid and Botox, it is due to the aging process. Therefore, there are people who see the effect last more than five years.
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Recognized by the world.Skin Rejuvenate Injections,
Microneeding Skin TreatmentPruge Beauty Clinic President has been researching regenerative treatment using prp since 2010, when PRP was not yet known to the general public.
A study was published in the international journal of tissue regeneration engineering, Tissue Engineering, in 2012.
In addition, the Act has been granted a special permit in the United States.
That is the reason why we can recommend Skin Rejuvenate Injections and Microneeding skin treatment with confidence.
The Four Features of Skin Rejuvenate Injections and
Microneeding Skin Treatment
Highly Effective
Skin RegenerationIt is highly concentrated, so you can get a different dimension of skin regeneration effect.
Long Lasting Effect
It rejuvenates the skin from the ground up, so the effect is long-lasting.
Highle Safe
Due to using your own blood, there are almost no side effects such as allergies.
Consideration of
PainThe use of blunt needles and anesthesia with an application is used to minimize the pain during the procedure.







Downtime, post-surgery, side effects and contraindications
Treatment Time | About 1 hour. |
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Anesthesia | Strong analgesics, ointment anesthesia, laughing gas, local anesthesia, nerve block injection, intravenous anesthesia, (optional) |
Side Effect | In rare cases, the injection site and surrounding area may be swell, but this will subside in 3-4 days. (Skin Rejuvenate Injections). Deeper puncture depths may result in redness and internal bleeding of the skin after the procedure for 2 to 3 days (Microneeding skin treatment). |
Bathing and Washing of Face | You can wash your face and shower after 30 minutes for Skin Rejuvenate Injections and after 6 hours for Microneeding skin treatment. Bathing to warm your body will be allowed from the next day. |
Make-up | For rejuvenate injections you can use it immediately after the treatment and and for Microneeding skin treatment 12 hours after the treatment. |
Contraindication |
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Surgical Area | 1 location | Additional charge for 2 or more locations |
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Dark Circles Under The Eyes, lines, doll blush, golgo lines, marionette lines, wrinkles at the corners of the eyes, wrinkles between the eyebrows, wrinkles at the base of the nose, and wrinkles around the mouth. | ¥89,000 | ¥25,000 |
Surgical Area | 1 location | Additional charge for 2 or more locations |
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Hollowing of the upper eyelids, lips, hooves, and neck wrinkles | ¥114,000 | ¥35,000 |
- The price is the same regardless of the amount of PRP injected.
- Since there is a limit to the amount of blood that can be drawn, the area that can be treated at the same time is limited.
- If you would like a part other than those above, please contact us.
Surgical Area | Pricing |
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Forehead | ¥198,000 |
Forehead + temples | ¥240,000 |
Temple | ¥168,000 |
Rejuvenate Heart Injection | ¥184,000 |
Rejuvenate Hand (both hands) | ¥186,000 |
Rejuvenate Hand (both hands) + Sclerotherapy (both hands) | ¥252,000 |
Relaxed anesthesia (IV) | ¥18,500 |


Surgical Area | One Time | 3 Sessions |
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Face all | ¥84,500 | ¥198,000 |
Surgical Area | One Time | 3 Sessions |
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1 part | ¥27,000 | ¥76,000 |
2 sites at the same time | ¥48,000 | ¥122,000 |
Simultaneous operation on 3 sites | ¥64,000 | ¥158,000 |
Approximate Part SizePlease contact us if you would like another part of the body.




3 minutes walk from JR Akabane Station,
2F Yamada Building, 2-15-10 Akabane, Kita-ku, Tokyo


Consultation hours |
Monday | Tuesday | Wednesday | Thursday | Friday | Saturday | Sunday |
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10:00 ~ 19:00 |
Closed: Monday and Thursday


- How long does the effect last?
- This treatment uses your own skin regeneration effect, so it will take about a month for the regeneration to be completed. After that, the effect will gradually increase over a period of 6 months to 1 year, and the condition will last for 3 to 4 years or more.
- How long do I have to wait to take the test again?
- If the next Skin Rejuvenate Injections are in the same area, the interval between injections should be at least 3 months, but if it is not in the same area, the procedure can be performed without the interval.Microneeding skin treatment is best spaced about 3 to 4 weeks apart.
- Can it be done at the same time as Microneeding skin treatment?
- It is necessary to leave more than a month for the area where you have had Skin Rejuvenate Injections. If you avoid the injection area, you can have the treatment at the same time.
- How is it different from hyaluronic acid?
- Skin Rejuvenate Injections are not only to add volume like hyaluronic acid, but also to regenerate the skin itself and improve the quality of the skin. In addition, Rejuvenate Injections are the best solution for wide areas of depressions such as forehead and cheekbones which are prone to be uneven when using hyaluronic acid.
- I've heard that it doesn't work for older people, is that true?
- It is generally believed that the activity rate of growth factors gradually decreases after their peak in the early twenties.However, with long-lasting, highly concentrated PRP, it is possible to rejuvenate the skin by using the maximum amount of regenerative power within your constitution.
- Can it be done at the same time as other treatments?
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As Skin Rejuvenate Injections improve skin texture and plump up the skin, when diagnosed as a symptom of skin laxity, it can be combined with other laxity treatments for a more pronounced rejuvenation effect.
Microneeding skin treatment can be performed at the same time as injections and suture lifts. Please allow at least 1 month for procedures that are highly irritating to the skin, such as skin cleansing laser, HIFU or fractional laser. - Who can't get the treatment?
- Since the procedure uses the patient's own blood, it is basically open to all patients regardless of age or constitution.
However, patients who are pregnant or lactating, or have a history of malignant tumors may not be able to undergo the procedure, so please consult with your doctor beforehand. - Can you clean up deep and prevalent acne scars?
- If it's the same part of the body, please leave more than 3 months, but if it's a different part of the body, the treatment can be done without a delay.



We believe that the goal of aesthetic medicine is to be close to patients' feelings and to help them have a richer life and happiness.
Age-related skin changes are often not a life-threatening, so when it comes time to seek treatment, you may be second-guessing yourself.
Many of you may still be concerned about the effectiveness, cost and safety of the program.
However, by eliminating the worries and complexes about your skin, you will feel more positive.
We believe that a change of heart is just as important as a treatment for a condition, in that a change of heart can lead to new opportunities and improve a person's life.
If you are interested in this service, please feel free to contact us regardless of whether you use the service or not.