0120-535-032 Clinic Hours:  10:00-19:00 (closed on Mondays and Thursdays)
Free treatment consultation and counseling. For reservations and inquiries, CLICK HERE

Treating wrinkles and indentations in your face from the source Restore your skin's elasticity and glow. REGENERATIVE MEDICINE Treating wrinkles and indentations in your face from the source Restore your skin's elasticity and glow. REGENERATIVE MEDICINE

Revived Beautiful Skin Cells Revived Beautiful Skin Cells
This treatment uses your own growth factors to maximize your skin's ability to regenerate.
Injected into the wrinkles and recesses of your face, you can get a natural volume increase and fresh firmness.
For Dark Circles Under The Eyes, sloping forehead, lines and more Skin Rejuvenate Injections For Dark Circles Under The Eyes, sloping forehead, lines and more Skin Rejuvenate Injections
  • Skin Rejuvenate Injections 01Skin Rejuvenate Injections 01

    Case Study42 year old Female

    SymptomsDark Circles Under The Eyes
    Treatment NameSkin Rejuvenate Injections (under the eyes)
    Approximate Rates97,000 JPY for both sides (include tax)
    Risks of the procedureIn rare cases, internal bleeding and swelling may occur.
  • Skin Rejuvenate Injections 02Skin Rejuvenate Injections 02

    Case Study28 year old Female

    SymptomsSloping forehead
    Treatment NameSkin Rejuvenate Injections (forehead)
    Approximate Rates198,000 JPY (include tax)
    Risks of the procedureIn rare cases, internal bleeding and swelling may occur.
  • Skin Rejuvenate Injections 03Skin Rejuvenate Injections 03

    Case Study28 year old Female

    SymptomsNascent lines
    Treatment NameSkin Rejuvenate Injections (nascent lines)
    Approximate Rates97,000 JPY (include tax)
    Risks of the procedureIn rare cases, internal bleeding and swelling may occur.
For skin problems such as dull skin, open pores, and acne scars Microneeding Skin Treatment For skin problems such as dull skin, open pores, and acne scars Microneeding Skin Treatment
  • Microneeding Skin Treatment 01Microneeding Skin Treatment 01

    Case Study24 year old Female

    SymptomsOpen pores
    Treatment NameMicroneeding skin treatment (cheek)
    Approximate Rates29,700 JPY (include tax)
    Risks of the procedureIn rare cases, internal bleeding and swelling may occur.
  • Microneeding Skin Treatment 02Microneeding Skin Treatment 02

    Case Study26 year old Female

    SymptomsOpen pores
    Treatment NameMicroneeding skin treatment (around the nose)
    Approximate Rates29,700 JPY (include tax)
    Risks of the procedureIn rare cases, internal bleeding and swelling may occur.
  • Microneeding Skin Treatment 03Microneeding Skin Treatment 03

    Case Study34 year old Female

    SymptomsOpen pores, dull skin and craters
    Treatment NameMicroneeding skin treatment (entire face)
    Approximate Rates84,500 JPY (include tax)
    Risks of the procedureIn rare cases, internal bleeding and swelling may occur.
What is Skin Rejuvenate Injections and Microneeding skin treatment ? What is Skin Rejuvenate Injections and Microneeding skin treatment ?

Regeneration of skin cells using the body's own blood

Skin Rejuvenate Injections, Microneeding skin treatment is an aesthetic skin regeneration treatment that uses multi-visceral blood vessels extracted from your own blood. Platelets contain high levels of natural growth factors, which activate various cells to regenerate and repair the tissue. As your own skin cells regenerate, the effect lasts for a long time, 3-4 years or more.

Drawing Blood > Growth Factor Extraction > Injections Into the SkinDrawing Blood > Growth Factor Extraction > Injections Into the Skin

Microneeding skin treatment uses a derma pen to create a myriad of microscopic holes in your skin to deliver PRP to the dermis and into the guilette. The synergistic effects of the dermis's self-damaging power and PRP's ability to produce beautiful skin components dramatically repair aging and acne-prone skin.

  • Derma Pen Derma Pen
    A derma pen is used to make microscopic holes in the dermis.
  • PRP to the dermis. Introduced to Guilect PRP to the dermis. Introduced to Guilect
    Penetration of PRP into the hole and introduction of PRP into the dermis
  • It increases the regenerative capacity of the dermis and renews the skin. It increases the regenerative capacity of the dermis and renews the skin.
    It increases the regenerative capacity of the dermis and renews the skin.
Not just any PRP will do! Not just any PRP will do!

The PRP used in Skin Rejuvenate Injections and Microneeding skin treatment is created by our own original method. Therefore, please note that even if you find similar treatments at other clinics, they may be fundamentally different from our treatments.

Our Skin Rejuvenate Injections are registered as a trademark.

Symptoms that can be improved with Skin Rejuvenate Injections and Microneeding skin treatment

This is the ultimate skin rejuvenation treatment, suitable for treating a wide variety of customes using your own blood, which is highly effective in improving skin quality with fewer allergic reactions. The production of collagen and elastin, which are the building blocks of the skin, is activated, resulting in natural volume growth and freshness and firmness.

Symptoms that can be improved Symptoms that can be improved

Start with
a free consultation

0120-535-032
Office hours: 10:00-19:00
(closed on Mondays and Thursdays)
For last minute reservations on the day, please call us to make a smooth reservation.
Skin Rejuvinate Injections & Microneeding Skin Treatment Web Reservation
Why Skin Rejuvenate Injections and Microneeding Skin Treatment are so effective Why Skin Rejuvenate Injections and Microneeding Skin Treatment are so effective
The PRP is just so dense! Compared to traditional PRP, Up to 30 times the concentration. The PRP is just so dense! Compared to traditional PRP, Up to 30 times the concentration.
Traditional PRP Skin Rejuvenate Injections &Microneeding skin treatment Traditional PRP Skin Rejuvenate Injections &Microneeding skin treatment
Here at Pruge Beauty Clinic, we have succeeded in raising the concentration used, said to have an upper limit of about 3 times, by our original centrifugal separation technology to an ultra-high concentration of up to 30 times.

Growth factors act in the fatty dermal layer of the dermis where PRP is injected to promote collagen and capillary growth, which gradually improves the appearance of depression and skin texture.

Why Skin Rejuvenate Injections and Microneeding Skin Treatment are so effective Why Skin Rejuvenate Injections and Microneeding Skin Treatment are so effective
  • The Skin Regeneration Effect Lasts more than 3 years!

    The Skin Regeneration Effect Lasts more than 3 years!

    Skin Rejuvenate Injections and Microneeding skin treatment lasts for 3 or 4 years, due to your own skin regenerating itself, with the dents and the improved skin texture lasting for 3 or 4 years, even if we say 3 or 4 years, the effect does not wear off like hyaluronic acid and Botox, it is due to the aging process. Therefore, there are people who see the effect last more than five years.

  • Recognized by the world.

    Recognized by the world.Skin Rejuvenate Injections,
    Microneeding Skin Treatment

    Pruge Beauty Clinic President has been researching regenerative treatment using prp since 2010, when PRP was not yet known to the general public.
    A study was published in the international journal of tissue regeneration engineering, Tissue Engineering, in 2012.
    In addition, the Act has been granted a special permit in the United States.
    That is the reason why we can recommend Skin Rejuvenate Injections and Microneeding skin treatment with confidence.

The Four Features of Skin Rejuvenate Injections and
Microneeding Skin Treatment

  • Point1Highly Effective
    Skin Regeneration

    It is highly concentrated, so you can get a different dimension of skin regeneration effect.

  • Point2Long Lasting Effect

    It rejuvenates the skin from the ground up, so the effect is long-lasting.

  • Point3Highle Safe

    Due to using your own blood, there are almost no side effects such as allergies.

  • Point4Consideration of
    Pain

    The use of blunt needles and anesthesia with an application is used to minimize the pain during the procedure.

Start with
a free consultation

0120-535-032
Office hours: 10:00-19:00
(closed on Mondays and Thursdays)
For last minute reservations on the day, please call us to make a smooth reservation.
Skin Rejuvinate Injections & Microneeding Skin Treatment Web Reservation
Case Studies
You Can Read More About
The Case Here
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An Uncompromising Commitment to Pain Relief An Uncompromising Commitment to Pain Relief
Depending on the area to be treated, the above anesthesia will be combined appropriately to minimize pain. Depending on the area to be treated, the above anesthesia will be combined appropriately to minimize pain.

Start with
a free consultation

0120-535-032
Office hours: 10:00-19:00
(closed on Mondays and Thursdays)
For last minute reservations on the day, please call us to make a smooth reservation.
Skin Rejuvinate Injections & Microneeding Skin Treatment Web Reservation
Flow of Treatment Flow of Treatment
  • Counseling1

    Counseling

    Please tell us as much as possible about the condition or area you would like to treat. We will recommend the best treatment for your symptoms.

    Please tell us as much as possible about the condition or area you would like to treat. We will recommend the best treatment for your symptoms.

  • Drawing blood2

    Drawing blood

    The blood is drawn for the preparation of PRP. The amount of blood drawn will vary depending on your request. You may still need to have a blood test before the procedure.

    The blood is drawn for the preparation of PRP. The amount of blood drawn will vary depending on your request. You may still need to have a blood test before the procedure.

  • PRP preparation3

    PRP preparation

    PRP is extracted from the prepared blood through a centrifuge. The prepared PRP can be viewed by you before the treatment.

    PRP is extracted from the prepared blood through a centrifuge. The prepared PRP can be viewed by you before the treatment.

  • Treatment4

    Treatment

    The prp is injected into the area where you want to regenerate the skin. For Microneeding skin treatment, a Dermapen is used to make very small holes in the entire face to penetrate the prp.

    The prp is injected into the area where you want to regenerate the skin. For Microneeding skin treatment, a Dermapen is used to make very small holes in the entire face to penetrate the prp.

  • Return home5

    Return home

    You can go home immediately after the procedure.

    You can go home immediately after the procedure.

Downtime, post-surgery, side effects and contraindications

Treatment TimeAbout 1 hour.
AnesthesiaStrong analgesics, ointment anesthesia, laughing gas, local anesthesia, nerve block injection, intravenous anesthesia, (optional)
Side EffectIn rare cases, the injection site and surrounding area may be swell, but this will subside in 3-4 days. (Skin Rejuvenate Injections). Deeper puncture depths may result in redness and internal bleeding of the skin after the procedure for 2 to 3 days (Microneeding skin treatment).
Bathing and Washing of FaceYou can wash your face and shower after 30 minutes for Skin Rejuvenate Injections and after 6 hours for Microneeding skin treatment. Bathing to warm your body will be allowed from the next day.
Make-upFor rejuvenate injections you can use it immediately after the treatment and and for Microneeding skin treatment 12 hours after the treatment.
Contraindication
  • For patients with cancer, history of cancer, cardiovascular disease, liver disease, and diabetes.
  • Pregnant or lactating women
  • Those with keloid constitution
Cost Cost
The cost of Skin Rejuvenate InjectionsThe cost of Skin Rejuvenate InjectionsPrices include tax
Surgical Area 1 location Additional charge for 2 or more locations
Dark Circles Under The Eyes, lines, doll blush, golgo lines, marionette lines, wrinkles at the corners of the eyes, wrinkles between the eyebrows, wrinkles at the base of the nose, and wrinkles around the mouth. ¥97,000 ¥27,500
Surgical Area 1 location Additional charge for 2 or more locations
Hollowing of the upper eyelids, lips, hooves, and neck wrinkles ¥125,400 ¥38,500
  • The price is the same regardless of the amount of PRP injected.
  • Since there is a limit to the amount of blood that can be drawn, the area that can be treated at the same time is limited.
  • If you would like a part other than those above, please contact us.
Surgical Area Pricing
Forehead ¥198,000
Forehead + temples ¥240,000
Temple ¥168,000
Rejuvenate Heart Injection ¥168,000
Rejuvenate Hand (both hands) ¥148,000
Rejuvenate Hand (both hands) + Sclerotherapy (both hands) ¥186,000
Relaxed anesthesia (IV) ¥35,000
The cost of a Microneeding skin treatmentThe cost of a Microneeding skin treatmentPrices include tax
Surgical Area One Time 3 Sessions
Face all ¥84,500 ¥198,000
Surgical Area One Time 3 Sessions
1 part ¥29,700 ¥83,600
2 sites at the same time ¥52,800 ¥134,200
Simultaneous operation on 3 sites ¥70,400 ¥173,800

Approximate Part SizePlease contact us if you would like another part of the body.

Cheek (one side), Your face line (on one side), Nose area, Chin, Forehead Cheek (one side), Your face line (on one side), Nose area, Chin, Forehead
Cheek (one side), Your face line (on one side), Nose area, Chin, Forehead
About Us
Access to the Clinic

3 minutes walk from JR Akabane Station,
2F Yamada Building, 2-15-10 Akabane, Kita-ku, Tokyo

  • Pruge Cosmetic Clinic Map
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Office hours and daysOffice hours and days
Consultation
hours
Monday Tuesday Wednesday Thursday Friday Saturday Sunday
10:00 ~ 19:00

Closed: Monday and Thursday

Start with
a free consultation

0120-535-032
Office hours: 10:00-19:00
(closed on Mondays and Thursdays)
For last minute reservations on the day, please call us to make a smooth reservation.
Skin Rejuvinate Injections & Microneeding Skin Treatment Web Reservation
Frequently Asked Questions Frequently Asked Questions
How long does the effect last?
This treatment uses your own skin regeneration effect, so it will take about a month for the regeneration to be completed. After that, the effect will gradually increase over a period of 6 months to 1 year, and the condition will last for 3 to 4 years or more.
How long do I have to wait to take the test again?
If the next Skin Rejuvenate Injections are in the same area, the interval between injections should be at least 3 months, but if it is not in the same area, the procedure can be performed without the interval.Microneeding skin treatment is best spaced about 3 to 4 weeks apart.
Can it be done at the same time as Microneeding skin treatment?
It is necessary to leave more than a month for the area where you have had Skin Rejuvenate Injections. If you avoid the injection area, you can have the treatment at the same time.
How is it different from hyaluronic acid?
Skin Rejuvenate Injections are not only to add volume like hyaluronic acid, but also to regenerate the skin itself and improve the quality of the skin. In addition, Rejuvenate Injections are the best solution for wide areas of depressions such as forehead and cheekbones which are prone to be uneven when using hyaluronic acid.
I've heard that it doesn't work for older people, is that true?
It is generally believed that the activity rate of growth factors gradually decreases after their peak in the early twenties.However, with long-lasting, highly concentrated PRP, it is possible to rejuvenate the skin by using the maximum amount of regenerative power within your constitution.
Can it be done at the same time as other treatments?
As Skin Rejuvenate Injections improve skin texture and plump up the skin, when diagnosed as a symptom of skin laxity, it can be combined with other laxity treatments for a more pronounced rejuvenation effect.

Microneeding skin treatment can be performed at the same time as injections and suture lifts. Please allow at least 1 month for procedures that are highly irritating to the skin, such as skin cleansing laser, HIFU or fractional laser.
Who can't get the treatment?
Since the procedure uses the patient's own blood, it is basically open to all patients regardless of age or constitution.
However, patients who are pregnant or lactating, or have a history of malignant tumors may not be able to undergo the procedure, so please consult with your doctor beforehand.
Can you clean up deep and prevalent acne scars?
If it's the same part of the body, please leave more than 3 months, but if it's a different part of the body, the treatment can be done without a delay.
For Patients Considering For Patients Considering
For Patients Considering
We believe that the goal of aesthetic medicine is to be close to patients' feelings and to help them have a richer life and happiness.

Age-related skin changes are often not a life-threatening, so when it comes time to seek treatment, you may be second-guessing yourself.
Many of you may still be concerned about the effectiveness, cost and safety of the program.
However, by eliminating the worries and complexes about your skin, you will feel more positive.
We believe that a change of heart is just as important as a treatment for a condition, in that a change of heart can lead to new opportunities and improve a person's life.
If you are interested in this service, please feel free to contact us regardless of whether you use the service or not.

Start with
a free consultation

0120-535-032
Office hours: 10:00-19:00
(closed on Mondays and Thursdays)
For last minute reservations on the day, please call us to make a smooth reservation.
Skin Rejuvinate Injections & Microneeding Skin Treatment Web Reservation